ING2 Protein (AA 1-280) (GST tag)

Catalog No. ABIN1307911

This Recombinant ING2 protein is produced in Wheat germ. There is 1 publication available.

Quick Overview for ING2 Protein (AA 1-280) (GST tag) (ABIN1307911)

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Protein Type: Recombinant

Origin: Human

Source: Wheat germ

Application: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Product Details

Protein Characteristics: AA 1-280

Purification tag / Conjugate: This ING2 protein is labelled with GST tag.

Purpose: ING2 (Human) Recombinant Protein (P01)

Sequence: MLGQQQQQLY SSAALLTGER SRLLTCYVQD YLECVESLPH DMQRNVSVLR ELDNKYQETL KEIDDVYEKY KKEDDLNQKK RLQQLLQRAL INSQELGDEK IQIVTQMLEL VENRARQMEL HSQCFQDPAE SERASDKAKM DSSQPERSSR RPRRQRTSES RDLCHMANGI EDCDDQPPKE KKSKSAKKKK RSKAKQEREA SPVEFAIDPN EPTYCLCNQV SYGEMIGCDN EQCPIEWFHF SCVSLTYKPK GKWYCPKCRG DNEKTMGKST EKTKKDRRSR

Characteristics: Human ING2 full-length ORF ( AAH30128, 1 a.a. - 280 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Ythier, Larrieu, Binet, Binda, Brambilla, Gazzeri, Pedeux: "Sumoylation of ING2 regulates the transcription mediated by Sin3A." in: Oncogene, Vol. 29, Issue 44, pp. 5946-56, (2010) (PubMed).

Target Details

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Alternative Name: ING2

Background: Full Gene Name: inhibitor of growth family, member 2
Synonyms: ING1L,p33ING2

Gene ID: 3622

Pathways: Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling