FABP4 Protein (AA 1-132) (His tag)

Catalog No. ABIN1344005

This Recombinant FABP4 protein is produced in Escherichia coli (E. coli).

Quick Overview for FABP4 Protein (AA 1-132) (His tag) (ABIN1344005)

Target: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: >90 % (SDS-PAGE)

Product Details

Protein Characteristics: AA 1-132

Purification tag / Conjugate: This FABP4 protein is labelled with His tag.

Purpose: FABP4 (human) (rec.) (His)

Cross-Reactivity: Human

Characteristics: Human FABP4 (aa 1-132) is fused at the C-terminus to a His-tag.

Sterility: Sterile filtered

Endotoxin Level: <1EU/μg purified protein (LAL test).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 200 mM NaCl.

Handling Advice: After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.

Storage: 4 °C,-20 °C

Storage Comment:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Expiry Date: 6 months

Target Details

Target: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Alternative Name: FABP4

Background:

Fatty Acid Binding Protein 4, Adipocyte Fatty Acid Binding Protein, ALBP, Adipocyte Lipid Binding Protein

FABP4 is a fatty acid binding protein in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs regulate the fatty acid uptake, transport, and metabolism. aP2, the mouse form of FABP4, seems to be central to the pathway that links obesity to insulin resistance. aP2 was shown to be an adipokine linking adipocytes to hepatic glucose production and that neutralizing secreted aP2 may represent an effective therapeutic strategy against diabetes.

Molecular Weight: ~16kDa (SDS-PAGE)

UniProt: P15090

Pathways: Brown Fat Cell Differentiation