TNFRSF21 Protein (AA 42-351) (Fc Tag)
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- Target See all TNFRSF21 Proteins
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 42-351
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TNFRSF21 protein is labelled with Fc Tag.
- Purpose
- DR6 (human):Fc (human) (rec)
- Cross-Reactivity
- Human
- Characteristics
- The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351).
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFRSF21 Protein
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Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-349) protein (His tag)
TNFRSF21 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-349) protein (His tag)TNFRSF21 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 373-655) protein (His-DYKDDDDK-Strep II Tag)TNFRSF21 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 47-349) protein (His-DYKDDDDK-Strep II Tag)TNFRSF21 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-349) protein (His tag)TNFRSF21 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-472) protein (GST tag)TNFRSF21 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-124) protein (GST tag)TNFRSF21 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- 1 mg/mL after reconstitution
- Concentration
- 1 mg/mL
- Buffer
- Contains PBS.
- Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1 % BSA should be used for further dilutions.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- Expiry Date
- 6 months
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- Target
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
- Alternative Name
- DR6 (TNFRSF21 Products)
- Background
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Tumor Necrosis Factor Receptor Superfamily Member 21, TNFRSF21, Death Receptor 6, CD358
DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.
- Molecular Weight
- ~80kDa (SDS-PAGE)
- UniProt
- O75509
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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