CD137 Protein (AA 1-185) (Fc Tag)
Quick Overview for CD137 Protein (AA 1-185) (Fc Tag) (ABIN1344189)
Target
See all CD137 (TNFRSF9) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-185
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Purification tag / Conjugate
- This CD137 protein is labelled with Fc Tag.
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Purpose
- CD137 (mouse):Fc (human) (rec.)
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Cross-Reactivity
- Mouse
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Characteristics
- The extracellular domain of mouse CD137 (aa 1-185) is fused at the C-terminus to the Fc portion of human IgG1.
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Sterility
- Sterile filtered
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Endotoxin Level
- <0.1EU/μg purified protein (LAL test).
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Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) (Active) protein (hFc-Avi Tag)
TNFRSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) (Active) protein (Biotin,His-Avi Tag)TNFRSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) protein (His tag,mFc Tag)TNFRSF9 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) (Active) protein (His tag)TNFRSF9 Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) (Active) protein (hFc-Avi Tag,Biotin)TNFRSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) protein (His-DYKDDDDK-Strep II Tag)TNFRSF9 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 46-128) protein (His-DYKDDDDK-Strep II Tag)TNFRSF9 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) protein (His tag)TNFRSF9 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-211) (Active) protein (His tag)TNFRSF9 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-211) protein (Fc Tag)TNFRSF9 Origin: Mouse Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.2μm filtered solution in PBS.
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Handling Advice
- After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 2 years after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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Expiry Date
- 24 months
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- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
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Alternative Name
- CD137
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Background
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4-1BB, TNFRSF9
CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.
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Molecular Weight
- ~50kDa (SDS-PAGE)
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UniProt
- P20334
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Pathways
- Cancer Immune Checkpoints
Target
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