ITLN1/Omentin Protein (AA 17-313) (DYKDDDDK Tag)

Catalog No. ABIN1344312

This Recombinant ITLN1/Omentin protein is expressed in CHO Cells.

Quick Overview for ITLN1/Omentin Protein (AA 17-313) (DYKDDDDK Tag) (ABIN1344312)

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: CHO Cells

Application: SDS-PAGE (SDS)

Purity: >95 % (SDS-PAGE)

Product Details

Protein Characteristics: AA 17-313

Purification tag / Conjugate: This ITLN1/Omentin protein is labelled with DYKDDDDK Tag.

Purpose: Omentin (human) (rec.)

Cross-Reactivity: Human

Characteristics: Human omentin (aa 17-313) is fused at the N-terminus to a FLAG®-tag.

Endotoxin Level: <0.1EU/μg purified protein (LAL test).

Biological Activity Comment: Enhances glucose transport mediated by insulin.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 100 μL sterile water.

Concentration: 0.1 mg/mL

Buffer: Contains PBS.

Handling Advice: After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.

Storage: 4 °C,-20 °C

Storage Comment:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Expiry Date: 6 months

Target Details

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Alternative Name: Omentin

Background:

Galactofuranose-binding Lectin, Intestinal Lactoferrin Receptor, Intelectin-1, ITLN1, Endothelial Lectin HL-1, Omentin 1

Omentin (Intelectin-1) is highly expressed in omental adipose tissue, small intestine and various other tissues. Omentin has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin. It was suggested to play a role in the defense system against microorganisms by recognizing carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues.

Molecular Weight: ~38kDa

UniProt: Q8WWA0