Caveolin-1 Protein (AA 1-178) (GST tag)

Catalog No. ABIN1348146

This Recombinant Caveolin-1 protein is expressed in Wheat germ and has been mentioned in 4+ publications.

Quick Overview for Caveolin-1 Protein (AA 1-178) (GST tag) (ABIN1348146)

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Protein Type: Recombinant

Origin: Human

Source: Wheat germ

Application: Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)

Product Details

Protein Characteristics: AA 1-178

Purification tag / Conjugate: This Caveolin-1 protein is labelled with GST tag.

Purpose: CAV1 (Human) Recombinant Protein (P01)

Sequence: MSGGKYVDSE GHLYTVPIRE QGNIYKPNNK AMADELSEKQ VYDAHTKEID LVNRDPKHLN DDVVKIDFED VIAEPEGTHS FDGIWKASFT TFTVTKYWFY RLLSALFGIP MALIWGIYFA ILSFLHIWAV VPCIKSFLIE IQCISRVYSI YVHTVCDPLF EAVGKIFSNV RINLQKEI

Characteristics: Human CAV1 full-length ORF ( AAH09685, 1 a.a. - 178 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Kastelijn, van Moorsel, Kazemier, Roothaan, Ruven, Kwakkel-van Erp, van de Graaf, Zanen, van Kessel, Grutters: "A genetic polymorphism in the CAV1 gene associates with the development of bronchiolitis obliterans syndrome after lung transplantation." in: Fibrogenesis & tissue repair, Vol. 4, pp. 24, (2011) (PubMed).

Bruyère, Abeloos, Lamoral-Theys, Senetta, Mathieu, Le Mercier, Kast, Cassoni, Vandenbussche, Kiss, Lefranc: "Temozolomide modifies caveolin-1 expression in experimental malignant gliomas in vitro and in vivo." in: Translational oncology, Vol. 4, Issue 2, pp. 92-100, (2011) (PubMed).

Xia, Khalil, Kahm, Jessurun, Kleidon, Henke: "Pathologic caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis." in: The American journal of pathology, Vol. 176, Issue 6, pp. 2626-37, (2010) (PubMed).

Sawada, Ishikawa, Tanji, Nakachi, Senba, Okudaira, Uchihara, Taira, Ohshiro, Yamada, Tanaka, Uezato, Ohshima, Sasai, Burgering, Duc Dodon, Fujii, Sunakawa, Mori: "Overexpression of caveolin-1 in adult T-cell leukemia." in: Blood, Vol. 115, Issue 11, pp. 2220-30, (2010) (PubMed).

Target Details

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Alternative Name: CAV1

Background: Full Gene Name: caveolin 1, caveolae protein, 22 kDa
Synonyms: BSCL3,CAV,CGL3,MSTP085,VIP21

Gene ID: 857

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals