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FcRn Protein (AA 51-160) (GST tag)

FcRn Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Catalog No. ABIN1353903
  • Target See all FcRn Proteins
    FcRn (neonatal Fc Receptor (FcRn))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 51-160
    Origin
    • 17
    • 6
    • 5
    • 3
    • 3
    • 1
    Human
    Source
    • 21
    • 5
    • 3
    • 1
    • 1
    • 1
    Wheat germ
    Purification tag / Conjugate
    This FcRn protein is labelled with GST tag.
    Application
    Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)
    Purpose
    FCGRT (Human) Recombinant Protein (Q01)
    Sequence
    GWLGPQQYLS YNSLRGEAEP CGAWVWENQV SWYWEKETTD LRIKEKLFLE AFKALGGKGP YTLQGLLGCE LGPDNTSVPT AKFALNGEEF MNFDLKQGTW GGDWPEALAI
    Characteristics
    Human FCGRT partial ORF ( AAH08734, 51 a.a. - 160 a.a.) recombinant protein with GST-tag at N-terminal.
    Purification
    in vitro wheat germ expression system
    Top Product
    Discover our top product FcRn Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Preparation method: in vitro, wheat germ expression system
    Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

    Restrictions
    For Research Use only
  • Buffer
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -80 °C
    Storage Comment
    Best use within three months from the date of receipt of this protein.
  • Deissler, Lang, Lang: "Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor." in: Experimental eye research, Vol. 143, pp. 49-59, (2015) (PubMed).

  • Target
    FcRn (neonatal Fc Receptor (FcRn))
    Alternative Name
    FCGRT (FcRn Products)
    Background
    Full Gene Name: Fc fragment of IgG, receptor, transporter, alpha
    Synonyms: FCRN,alpha-chain
    Gene ID
    2217
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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