Estrogen Receptor alpha Protein (AA 10-595) (His tag)

Catalog No. ABIN7478954

Recombinant Estrogen Receptor alpha protein expressed in Yeast.

Quick Overview for Estrogen Receptor alpha Protein (AA 10-595) (His tag) (ABIN7478954)

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Protein Type: Recombinant

Origin: Human

Source: Yeast

Application: ELISA

Purity: > 90 %

Product Details

Protein Characteristics: AA 10-595

Purification tag / Conjugate: This Estrogen Receptor alpha protein is labelled with His tag.

Sequence: SGMALLHQIQ GNELEPLNRP QLKIPLERPL GEVYLDSSKP AVYNYPEGAA YEFNAAAAAN AQVYGQTGLP YGPGSEAAAF GSNGLGGFPP LNSVSPSPLM LLHPPPQLSP FLQPHGQQVP YYLENEPSGY TVREAGPPAF YRPNSDNRRQ GGRERLASTN DKGSMAMESA KETRYCAVCN DYASGYHYGV WSCEGCKAFF KRSIQGHNDY MCPATNQCTI DKNRRKSCQA CRLRKCYEVG MMKGGIRKDR RGGRMLKHKR QRDDGEGRGE VGSAGDMRAA NLWPSPLMIK RSKKNSLALS LTADQMVSAL LDAEPPILYS EYDPTRPFSE ASMMGLLTNL ADRELVHMIN WAKRVPGFVD LTLHDQVHLL ECAWLEILMI GLVWRSMEHP GKLLFAPNLL LDRNQGKCVE GMVEIFDMLL ATSSRFRMMN LQGEEFVCLK SIILLNSGVY TFLSSTLKSL EEKDHIHRVL DKITDTLIHL MAKAGLTLQQ QHQRLAQLLL ILSHIRHMSN KGMEHLYSMK CKNVVPLYDL LLEMLDAHRL HAPTSRGGAS VEETDQSHLA TAGSTSSHSL QKYYITGEAE GFPAT

Specificity: Homo sapiens (Human)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Alternative Name: Estrogen receptor (ESR1)

Background: Recommended name: Estrogen receptor.
Short name= ER.
Alternative name(s): ER-alpha Estradiol receptor Nuclear receptor subfamily 3 group A member 1

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly