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SRY Protein

Recombinant SRY protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN1589734

Quick Overview for SRY Protein (ABIN1589734)

Target

See all SRY Proteins
SRY (Sex Determining Region Y (SRY))

Protein Type

Recombinant

Origin

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Cow

Source

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Escherichia coli (E. coli)

Purity

> 90 % by SDS-PAGE. Visualized by silver stain
  • Sequence

    MFRVLNDDVY SPAVVQQQTT LAFRKDSSLC TDSHSANDQC ERGEHVRESS QDHVKRPMNA FIVWSRERRR KVALENPKMK NSDISKQLGY EWKRLTDAEK RPFFEEAQRL LAIHRDKYPG YKYRPRRRAK RPQKSLPADS SILCNPMHVE TLHPFTYRDG CAKTTYSQME SQLSRSQSVI ITNSLLQKEH HSSWTSLGHN KVTLATRISA DFPCNKSLEP GLSCAYFQYL E

    Characteristics

    Length (AA): 231
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  • Application Notes

    No biological data available at the moment.

    Comment

    Cytokines & Growth Factors

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Bovine SRY should be reconstituted in PBS to a concentration of 0.1 mg/mL. This solution can be diluted in water or other buffer solutions or stored at -20 °C.

    Buffer

    water

    Storage

    -20 °C

    Storage Comment

    The lyophilized powder although stable at room temperature for 3 weeks, is best stored desiccated at -20 °C. Reconstituted bo SRY should be stored in working aliquots at -20 °C. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA).

    Expiry Date

    3 weeks at RT
  • Target

    SRY (Sex Determining Region Y (SRY))

    Alternative Name

    SRY

    Background

    The „Sex determining region of Y-Gen” (SRY), known as SRY gene, is coding for a transkription factor (TDF for Testis-determining factor). It belongs to the protein family of DNA binding-proteins. The SRY gene is beside other genes used for the determination of the sex in human as well as other mammals. Most mammals have for this purpose a further gene, UBE1. In humans SRY is normally located on the short arm of the Y chromosome. Accordingly, people who possess this chromosome with the corresponding gene, normally have a male phenotype. It does not matter how many copies of the X chromosome are present, even people with a multiple X chromosome (Klinefelter's syndrome) have this. The protein encoded by the gene Testis-determining factor controls the development of male sex
    Synonyms: Sex-determining region Y protein, Testis-determining factor

    Molecular Weight

    26.8 kDa

    NCBI Accession

    NM_001014385, NP_001014407

    UniProt

    Q03255
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