LGALS1/Galectin 1 Protein

Catalog No. ABIN1589772

This Recombinant LGALS1/Galectin 1 protein is expressed in Escherichia coli (E. coli).

Quick Overview for LGALS1/Galectin 1 Protein (ABIN1589772)

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % by SDS-PAGE and visualized by Coomassie stain

Product Details

Purpose: Galectin-1

Sequence: ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPF QPGSVAEVCI T FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFDLEHHHH HH

Specificity: Chromosomal location:22q13.1

Characteristics: Length (aa):142

Application Details

Comment:

Cytokines & Growth Factors

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Human Galectin-1 should be reconstituted in water to a concentration of 0.1 mg/mL. This solution can be diluted in water or other buffer solutions or stored at -20 °C.

Buffer: PBS

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: RT,0 °C,-20 °C

Storage Comment: The lyophilized human Galectin-1, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted human Galectin-1 should be stored in working aliquots at -20°C.

Target Details

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Alternative Name: Galectin-1

Background: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.
Synonyms: LGALS1, GBP, GAL1

Molecular Weight: 14,5 kDa

Gene ID: 3956

NCBI Accession: NM_002305, NP_002296

UniProt: P09382

Pathways: Carbohydrate Homeostasis