NR1H2 Protein (AA 1-455) (His tag)

Catalog No. ABIN7589812

This Recombinant NR1H2 protein is expressed in Yeast.

Quick Overview for NR1H2 Protein (AA 1-455) (His tag) (ABIN7589812)

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Protein Type: Recombinant

Origin: Cow

Source: Yeast

Application: ELISA

Purity: > 90 %

Product Details

Protein Characteristics: AA 1-455

Purification tag / Conjugate: This NR1H2 protein is labelled with His tag.

Sequence: MSTPTTNSVD TPLPGNGPST PSSSPGGKED GPEPCPGGAD PDVPSTDGAD SASVVVILDT AEEPERKRKK GPAPKMLGDE LCQVCGDTAS GFHYNVLSCE GCKGFFRRSV IRGGAGRYAC RGGGTCQMDA FMRRKCQQCR LRKCKEAGMR EQCVLSKEQI RKKKIRKQQQ QQQQQSSPTG PGVSSSSPAS GPGASPGGSD GGGQGSGEGE GVQLTAAQEL MIQQLVAAQL QCNKRSFSDQ PKVTPWPLGA DPQSRDARQQ RFAHFTELAI ISVQEIVDFA KQVPGFLQLG REDQIALLKA STIEIMLLET ARRYNHETEC ITFLKDFTYS KDDFHRAGLQ VEFINPIFEF SRAMRRLGLD DAEYALLIAI NIFSADRPNV QEPSRVEALQ QPYVDALLSY TRIKRPQDQL RFPRMLMKLV SLRTLSSVHS EQVFALRLQD KKLPPLLSEI WDVHE

Specificity: Bos taurus (Bovine)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Alternative Name: Oxysterols receptor LXR-beta (NR1H2)

Background: Recommended name: Oxysterols receptor LXR-beta.
Alternative name(s): Liver X receptor beta Nuclear receptor subfamily 1 group H member 2

UniProt: Q5BIS6

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding