NR1H2 Protein (Myc-DYKDDDDK Tag)
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- Target See all NR1H2 Proteins
- NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NR1H2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NR1H2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NR1H2 Protein
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Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2) (AA 1-461) protein (GST tag)
NR1H2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2) (AA 1-460) protein (Strep Tag)Crystallography grade NR1H2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2) (AA 1-446) protein (Strep Tag)Crystallography grade NR1H2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))
- Alternative Name
- Nr1h2 (NR1H2 Products)
- Synonyms
- NR1H2 Protein, lxr-b Protein, lxrb Protein, ner Protein, ner-i Protein, rip15 Protein, unr Protein, DKFZp468A0622 Protein, AI194859 Protein, LXR Protein, LXRB Protein, LXRbeta Protein, NER1 Protein, OR-1 Protein, RIP15 Protein, UR Protein, Unr Protein, Unr2 Protein, LXR-b Protein, NER Protein, NER-I Protein, UNR Protein, nuclear receptor subfamily 1 group H member 2 Protein, nuclear receptor subfamily 1, group H, member 2 Protein, nuclear receptor subfamily 1 group H member 2 L homeolog Protein, NR1H2 Protein, nr1h2 Protein, Nr1h2 Protein, nr1h2.L Protein
- Background
- The liver X receptors, LXRA (NR1H3 MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010].
- Molecular Weight
- 50.9 kDa
- NCBI Accession
- NP_009052
- Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding
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