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CD38 Protein (C-Term, Extracellular Domain)

This Recombinant CD38 protein is produced in HEK-293T Cells.
Catalog No. ABIN1684676

Quick Overview for CD38 Protein (C-Term, Extracellular Domain) (ABIN1684676)

Target

See all CD38 Proteins
CD38

Protein Type

Recombinant

Origin

  • 26
  • 9
  • 5
  • 3
  • 1
Mouse

Source

  • 18
  • 10
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
HEK-293T Cells

Purity

> 95 %, as determined by SDS-PAGE and HPLC
  • Protein Characteristics

    C-Term, Extracellular Domain

    Specificity

    Optimized DNA sequence encoding extracellular domain of mouse CD38 including a C-terminal 6His tag was expressed in HEK293 cells.

    Characteristics

    Recombinant mouse CD38 is a monomer protein consisting of69 amino acid residue subunits, due to glycosylation migrates as an approximately 45 kDa protein on SDS-PAGE.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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    Product
    Expression System
    Conjugate
    Origin
    Price starts at
    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Mouse
    Price starts at $16,231.82
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Mouse
    Price starts at $18,117.43

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  • Restrictions

    For Research Use only
  • Buffer

    PBS solution, pH7.2

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.

    Expiry Date

    12-24 months
  • Target

    CD38

    Background

    Resistin Resistin was identified by screening for genes that are induced during the differentiation of adipocytes but down-regulated in mature adipocytes. Resistin gene expression is induced during the differentiation of adipocytes. Resistin circulates in mouse serum, and its level is increased markedly in obesity. Adipocytes secrete resistin as a unique signaling molecule that may be the hormone potentially linking obesity to type II diabetes, which is characterized by target-tissue resistance to insulin. TNF-alpha is a negative regulator of Resistin gene expression and inhibits Resistin mRNA expression and protein secretion by 70-90 % in 3T3-L1 adipocytes.

    UniProt

    P56528
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