CD38 Protein (C-Term, Extracellular Domain)
Quick Overview for CD38 Protein (C-Term, Extracellular Domain) (ABIN1684676)
Target
See all CD38 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- C-Term, Extracellular Domain
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Specificity
- Optimized DNA sequence encoding extracellular domain of mouse CD38 including a C-terminal 6His tag was expressed in HEK293 cells.
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Characteristics
- Recombinant mouse CD38 is a monomer protein consisting of69 amino acid residue subunits, due to glycosylation migrates as an approximately 45 kDa protein on SDS-PAGE.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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Restrictions
- For Research Use only
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Buffer
- PBS solution, pH7.2
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.
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Expiry Date
- 12-24 months
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- CD38
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Background
- Resistin Resistin was identified by screening for genes that are induced during the differentiation of adipocytes but down-regulated in mature adipocytes. Resistin gene expression is induced during the differentiation of adipocytes. Resistin circulates in mouse serum, and its level is increased markedly in obesity. Adipocytes secrete resistin as a unique signaling molecule that may be the hormone potentially linking obesity to type II diabetes, which is characterized by target-tissue resistance to insulin. TNF-alpha is a negative regulator of Resistin gene expression and inhibits Resistin mRNA expression and protein secretion by 70-90 % in 3T3-L1 adipocytes.
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UniProt
- P56528
Target
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