TXN2 Protein (AA 60-166) (His tag)

Catalog No. ABIN1690923

Product Details

Target: TXN2 (Thioredoxin 2 (TXN2))

Protein Type: Recombinant

Protein Characteristics: AA 60-166

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This TXN2 protein is labelled with His tag.

Purpose: Recombinant Human Thioredoxin-2/TXN2 (N-6His)

Sequence: MTTFNIQDGP DFQDRVVNSE TPVVVDFHAQ WCGPCKILGP RLEKMVAKQH GKVVMAKVDI DDHTDLAIEY EVSAVPTVLA MKNGDVVDKF VGIKDEDQLE AFLKKLIG

Characteristics: Recombinant Human Thioredoxin-2/TXN2 is produced with our E. coli expression system. The target protein is expressed with sequence (Thr60-Gly166) of Human TXN2.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: TXN2 (Thioredoxin 2 (TXN2))

Alternative Name: Thioredoxin-2/Trx-2/MTRX (TXN2 Products)

Background: Thioredoxin-2 (TXN2) is a mitochondrial member of the thioredoxin family. Thioredoxin-2 is extensively expressed in adult and fetal tissues. Thioredoxin-2 contains an N-terminal 59 amino acid transit peptide, which is cleaved before translocating to mitochondria. Mitochondrial thioredoxin play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Thioredoxin-2 could be involved in the resistance to anti-tumor agents and possesses a dithiol-reducing activity. In addition, Thioredoxin-2 is important at low oxidative stress conditions.
Alternative Names: Thioredoxin Mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2

Molecular Weight: 12 kDa

UniProt: Q99757

Pathways: Cell RedoxHomeostasis