Cathepsin L2 Protein (CTSL2) (AA 18-334) (His tag)

Catalog No. ABIN1691179

This Recombinant Cathepsin L2 protein is produced in Human Cells.

Quick Overview for Cathepsin L2 Protein (CTSL2) (AA 18-334) (His tag) (ABIN1691179)

Target: Cathepsin L2 (CTSL2)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 18-334

Purification tag / Conjugate: This Cathepsin L2 protein is labelled with His tag.

Purpose: Recombinant Human Cathepsin L2/CTSL2 (C-6His)

Sequence: VPKFDQNLDT KWYQWKATHR RLYGANEEGW RRAVWEKNMK MIELHNGEYS QGKHGFTMAM NAFGDMTNEE FRQMMGCFRN QKFRKGKVFR EPLFLDLPKS VDWRKKGYVT PVKNQKQCGS CWAFSATGAL EGQMFRKTGK LVSLSEQNLV DCSRPQGNQG CNGGFMARAF QYVKENGGLD SEESYPYVAV DEICKYRPEN SVANDTGFTV VAPGKEKALM KAVATVGPIS VAMDAGHSSF QFYKSGIYFE PDCSSKNLDH GVLVVGYGFE GANSNNSKYW LVKNSWGPEW GSNGYVKIAK DKNNHCGIAT AASYPNVVDH HHHHH

Characteristics:

Recombinant Human Cathepsin L2/CTSL2 (C-6His)

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: Cathepsin L2 (CTSL2)

Alternative Name: Cathepsin L2

Background: Recombinant Human Cathepsin L2 produced by transfected human cells is a secreted protein with sequence (Val18-Val384) of Human CTSL2 fused with a polyhistidine tag at the C-terminus.
Cathepsin L2 belongs to the Peptidase C1 family. Cathepsin L2 can be autocatalytically converted to the mature form as a proenzyme in lysosomes at pH=7.0. Cathepsin L2 cannot be expressed in normal mammary gland, colon and peritumoral tissue, but it can be expressed in breast carcinomas and colorectal tissues. These suggeats Cathepsin L2 may play a role in tumor processes. Cathepsin L2 is specifically expressed in the testis, thymus, and corneal epithelium.

Molecular Weight: 36.69 kDa

UniProt: O60911

Pathways: Toll-Like Receptors Cascades