Uroplakin 2 Protein (UPK2) (AA 26-155) (His tag)

Catalog No. ABIN1691375

This Recombinant Uroplakin 2 protein is expressed in Human Cells.

Quick Overview for Uroplakin 2 Protein (UPK2) (AA 26-155) (His tag) (ABIN1691375)

Target: Uroplakin 2 (UPK2)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 26-155

Purification tag / Conjugate: This Uroplakin 2 protein is labelled with His tag.

Purpose: Recombinant Human Uroplakin-2/UPK2 (C-6His)

Sequence: DFNISSLSGL LSPALTESLL VALPPCHLTG GNATLMVRRA NDSKVVTSSF VVPPCRGRRE LVSVVDSGAG FTVTRLSAYQ VTNLVPGTKF YISYLVKKGT ATESSREIPM STLPRRNMES IGLGMARTGG VDHHHHHH

Characteristics: Recombinant Human Uroplakin-2/UPK2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asp26-Gly155) of Human UPK2 fused with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Uroplakin 2 (UPK2)

Alternative Name: Uroplakin-2

Sub Type: Fusionprotein

Background: Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER). Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the urothelium by preventing cell rupture during bladder distention.
Alternative Names: Uroplakin-2, UP2, Uroplakin II, UPII, UPK2

Molecular Weight: 14.84 kDa

UniProt: O00526