HPGDS Protein (AA 1-199)
Quick Overview for HPGDS Protein (AA 1-199) (ABIN1692116)
Target
See all HPGDS ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 1-199
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Purpose
- Recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS/GSTS
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Sequence
- MPNYKLTYFN MRGRAEIIRY IFAYLDIQYE DHRIEQADWP EIKSTLPFGK IPILEVDGLT LHQSLAIARY LTKNTDLAGN TEMEQCHVDA IVDTLDDFMS CFPWAEKKQD VKEQMFNELL TYNAPHLMQD LDTYLGGREW LIGNSVTWAD FYWEICSTTL LVFKPDLLDN HPRLVTLRKK VQAIPAVANW IKRRPQTKL
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Characteristics
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Recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS/GSTS
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Hematopoietic Prostaglandin D Synthase (HPGDS) (AA 1-199) protein (His tag)
custom-made HPGDS Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Hematopoietic Prostaglandin D Synthase (HPGDS) (AA 1-199) protein (His tag)custom-made HPGDS Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Hematopoietic Prostaglandin D Synthase (HPGDS) (AA 2-199) protein (His tag)HPGDS Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 200 mM NaCl, pH 7.0.
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Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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Storage
- -80 °C
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Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. -
Expiry Date
- 6 months
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- HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))
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Alternative Name
- Hematopoietic Prostaglandin D Synthase
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Background
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Recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS is produced with our E. coli expression system. The target protein is expressed with sequence (Pro2-Leu199) of Human PGDS.
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide. -
Molecular Weight
- 23.6 kDa
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UniProt
- O60760
Target
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