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HPGDS Protein (AA 1-199)

HPGDS Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1692117
  • Target See all HPGDS Proteins
    HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-199
    Origin
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS/GSTS
    Sequence
    MPNYKLTYFN MRGRAEIIRY IFAYLDIQYE DHRIEQADWP EIKSTLPFGK IPILEVDGLT LHQSLAIARY LTKNTDLAGN TEMEQCHVDA IVDTLDDFMS CFPWAEKKQD VKEQMFNELL TYNAPHLMQD LDTYLGGREW LIGNSVTWAD FYWEICSTTL LVFKPDLLDN HPRLVTLRKK VQAIPAVANW IKRRPQTKL
    Characteristics

    Recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS/GSTS

    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product HPGDS Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 200 mM NaCl, pH 7.0.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    -80 °C
    Storage Comment
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))
    Alternative Name
    Hematopoietic Prostaglandin D Synthase (HPGDS Products)
    Synonyms
    GSTS Protein, GSTS1-1 Protein, PGD2 Protein, PGDS Protein, L-PGDS Protein, LPGDS Protein, PDS Protein, PGDS2 Protein, XlGSTS1 Protein, gsts Protein, pgds Protein, H-PGDS Protein, Ptgds2 Protein, hpgds Protein, hpgds-a Protein, hpgds-b Protein, hpgdsa Protein, hematopoietic prostaglandin D synthase Protein, prostaglandin D2 synthase Protein, hematopoietic prostaglandin D synthase L homeolog Protein, HPGDS Protein, PTGDS Protein, hpgds Protein, Hpgds Protein, hpgds.L Protein
    Background
    Recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS is produced with our E. coli expression system. The target protein is expressed with sequence (Pro2-Leu199) of Human PGDS.
    Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide.
    Molecular Weight
    23.6 kDa
    UniProt
    O60760
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