CXCL16 Protein (AA 27-201, C-Term) (GST tag)

Catalog No. ABIN1692305

This Recombinant CXCL16 protein is produced in Escherichia coli (E. coli).

Quick Overview for CXCL16 Protein (AA 27-201, C-Term) (GST tag) (ABIN1692305)

Target: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Protein Type: Recombinant

Origin: Schistosoma japonicum

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: C-Term, AA 27-201

Purification tag / Conjugate: This CXCL16 protein is labelled with GST tag.

Purpose: Recombinant Schistosoma Japonicum Glutathione S-transferase Class-mu 26 kDa Isozyme/GST

Sequence: MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD

Characteristics: Tag: C-6His

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Alternative Name: C-X-C Motif Chemokine 16/CXCL16

Background: Recombinant Mouse C-X-C Motif Chemokine 16/CXCL16 is produced with our HEK293 expression system. The target protein is expressed with sequence (Asn27-Trp201) of Mouse CXCL16 fused with a 6His tag at the C-terminus.
C-X-C Motif Chemokine 16 (CXCL16) belongs to the intercrine α (chemokine CxC) family. CXCL16 is a single-pass type I membrane protein, which consists of 246 AAs. CXCL16 induces a strong chemotatic response and calcium mobilization. CXCL16 acts as a scavenger receptor on macrophages, which specially binds to oxidized low density lipoprotein. CXCL16 may be involved in pathophysiology such as atherogenesis. Soluble CXCL16 may play an important role in liver metastases through the induction of epithelial-mesenchymal transition.

Molecular Weight: 25.7 kDa

UniProt: P08515