Glypican 3 Protein (GPC3)
Quick Overview for Glypican 3 Protein (GPC3) (ABIN1880377)
Target
See all Glypican 3 (GPC3) ProteinsProtein Type
Origin
Source
Purity
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
Glypican 3 (GPC3) (AA 25-559) protein (His tag)
GPC3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 3 (GPC3) (AA 25-559) protein (His tag)GPC3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 3 (GPC3) (AA 25-559) protein (His-Avi Tag,Biotin)GPC3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 3 (GPC3) protein (Fc Tag)GPC3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Glypican 3 (GPC3) (AA 438-554) (Active) protein-VLPGPC3 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC Imm, ELISA, Func, SPR Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (Fc Tag)GPC3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE Func Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (Fc Tag)GPC3 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE Func Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (His tag)GPC3 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (His tag,AVI tag,Biotin)GPC3 Origin: Human Host: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Glypican 3 (GPC3) protein (His tag)GPC3 Origin: Mouse Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- 10 mM Tris-HCL (pH 8.8 +/- 0.2) with 0.05 % sodium azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
-
Storage
- 4 °C
-
-
- Glypican 3 (GPC3)
-
Alternative Name
- Glypican-3
-
Background
- Glypican 3, GPC3 is a member of the glypican family that are heparan sulfate proteoglycans that bind to the exocytoplasmic surface of the plasma membrane through a covalent glycosylphosphatidylinositol (GPI) linkage. GPC3 gene contains 8 exons and encompasses approximately 500 kb. It encodes a putative extracellular proteoglycan, glypican 3, that is inferred to play an important role in growth control in embryonic mesodermal tissues in which it is selectively expressed. GPC3 acts as a negative regulator of Hedgehog signaling during mammalian development and that the overgrowth observed in SGBS (Simpson-Golabi-Behmel overgrowth syndrome) patients is, at least in part, the consequence of hyperactivation of the Hedgehog signaling pathway.
-
Pathways
- Glycosaminoglycan Metabolic Process
Target
-
