FKBP2 Protein (AA 22-142) (His tag)
Quick Overview for FKBP2 Protein (AA 22-142) (His tag) (ABIN1880661)
Target
See all FKBP2 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 22-142
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Purification tag / Conjugate
- This FKBP2 protein is labelled with His tag.
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Purpose
- Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP2/FKBP22/FKBP13 (C-6His)
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Sequence
- ATGAEGKRKL QIGVKKRVDH CPIKSRKGDV LHMHYTGKLE DGTEFDSSLP QNQPFVFSLG TGQVIKGWDQ GLLGMCEGEK RKLVIPSELG YGERGAPPKI PGGATLVFEV ELLKIERRTE LVDHHHHHH
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Characteristics
- Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP2/FKBP2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala22-Leu142) of Human FKBP2 fused with a polyhistidine tag at the C-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150mm NaCl, pH 7.5.
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Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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Storage
- -80 °C
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Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. -
Expiry Date
- 6 months
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- FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))
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Alternative Name
- FKBP2
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Sub Type
- Fusionprotein
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Background
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Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 functions as an ER chaperone and as a component of membrane cytoskeletal scaffolds.
Alternative Names: Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. -
Molecular Weight
- 14.3 kDa
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UniProt
- P26885
Target
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