alpha KGDHC Protein (AA 41-1023) (His tag)

Catalog No. ABIN1945412

This Recombinant alpha KGDHC protein is expressed in HEK-293T Cells.

Quick Overview for alpha KGDHC Protein (AA 41-1023) (His tag) (ABIN1945412)

Target: alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

Protein Type: Recombinant

Origin: Human

Source: HEK-293T Cells

Application: SDS-PAGE (SDS)

Product Details

Protein Characteristics: AA 41-1023

Purification tag / Conjugate: This alpha KGDHC protein is labelled with His tag.

Sequence: SAPVAAEPFL SGTSSNYVEE MYCAWLENPK SVHKSWDIFF RNTNAGAPPG TAYQSPLPLS RGSLAAVAHA QSLVEAQPNV DKLVEDHLAV QSLIRAYQIR GHHVAQLDPL GILDADLDSS VPADIISSTD KLGFYGLDES DLDKVFHLPT TTFIGGQESA LPLREIIRRL EMAYCQHIGV EFMFINDLEQ CQWIRQKFET PGIMQFTNEE KRTLLARLVR STRFEEFLQR KWSSEKRFGL EGCEVLIPAL KTIIDKSSEN GVDYVIMGMP HRGRLNVLAN VIRKELEQIF CQFDSKLEAA DEGSGDVKYH LGMYHRRINR VTDRNITLSL VANPSHLEAA DPVVMGKTKA EQFYCGDTEG KKVMSILLHG DAAFAGQGIV YETFHLSDLP SYTTHGTVHV VVNNQIGFTT DPRMARSSPY PTDVARVVNA PIFHVNSDDP EAVMYVCKVA AEWRSTFHKD VVVDLVCYRR NGHNEMDEPM FTQPLMYKQI RKQKPVLQKY AELLVSQGVV NQPEYEEEIS KYDKICEEAF ARSKDEKILH IKHWLDSPWP GFFTLDGQPR SMSCPSTGLT EDILTHIGNV ASSVPVENFT IHGGLSRILK TRGEMVKNRT VDWALAEYMA FGSLLKEGIH IRLSGQDVER GTFSHRHHVL HDQNVDKRTC IPMNHLWPNQ APYTVCNSSL SEYGVLGFEL GFAMASPNAL VLWEAQFGDF HNTAQCIIDQ FICPGQAKWV RQNGIVLLLP HGMEGMGPEH SSARPERFLQ MCNDDPDVLP DLKEANFDIN QLYDCNWVVV NCSTPGNFFH VLRRQILLPF RKPLIIFTPK SLLRHPEARS SFDEMLPGTH FQRVIPEDGP AAQNPENVKR LLFCTGKVYY DLTRERKARD MVGQVAITRI EQLSPFPFDL LLKEVQKYPN AELAWCQEEH KNQGYYDYVK PRLRTTISRA KPVWYAGRDP AAAPATGNKK THLTELQRLL DTAFDLDVFK NFSVDHHHHH H*

Characteristics: Recombinant Human 2-oxoglutarate dehydrogenase, mitochondrial/OGDH is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (AA 41-1023) of Human OGDH fused with a polyhistidine tag at the C-termin

Sterility: 0.2 μm filtered

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a 0.2 μM filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol,pH7.5

Storage: -20 °C

Target Details

Target: alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

Alternative Name: OGDH

Background: OGDH, also known as 2-oxoglutarate dehydrogenase complex component E1 or Alpha-ketoglutarate dehydrogenase, is short for 2-oxoglutarate dehydrogenase, mitochondrial. It is a 1023 aa. protein, the first 40 aa. of which is a transit peptide. OGDH is usually located in the mitochondrion, and belongs to the pha-ketoglutarate dehydrogenase family. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).

UniProt: Q02218