ADIPOQ Protein (AA 21-247)
Quick Overview for ADIPOQ Protein (AA 21-247) (ABIN2017656)
Target
See all ADIPOQ ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 21-247
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Characteristics
- ED50 < 5 μg/mL, measured by a cell growth inhibitory assay using M1 cells, corresponding to a specific activity of > 2x 10^2 units/mg.
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Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Adiponectin (ADIPOQ) (Active) protein
ADIPOQ Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Adiponectin (ADIPOQ) (AA 19-244) protein (His tag)ADIPOQ Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Adiponectin (ADIPOQ) (AA 18-247) protein (His tag)ADIPOQ Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Adiponectin (ADIPOQ) (AA 19-244) protein (Fc Tag)ADIPOQ Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Adiponectin (ADIPOQ) (AA 18-247) protein (Fc Tag)ADIPOQ Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Adiponectin (ADIPOQ) protein (His tag)ADIPOQ Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Adiponectin (ADIPOQ) (AA 111-247) protein (His tag)ADIPOQ Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Adiponectin (ADIPOQ) (AA 111-247) proteinADIPOQ Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Adiponectin (ADIPOQ) (AA 111-210) protein (GST tag)ADIPOQ Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant mouse Adiponectin (rmAdiponectin) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmAdiponectin remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
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Expiry Date
- 6 months
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- ADIPOQ (Adiponectin (ADIPOQ))
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Alternative Name
- Adiponectin
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Background
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Adiponectin is a hormone mainly produced by adipocytes. Adiponectin forms a homotrimer and exists as higher order multimers in vivo. The receptors of Adiponectin are seven transmembrane G protein coupled receptors: Receptor 1 is expressed in skeletal muscle and Receptor 2 in liver. Adiponectin receives a lot of attention because of its anti-diabetic, anti-atherosclerotic, and anti-inflammatory properties. Adiponectin increases the expression of molecules involved in fatty acid transport, combustion of fatty acid, and energy dissipation, and increases insulin sensitivity of the body. Decreased levels of Adiponectin are associated with hypertension, cardiovascular diseases, and metabolic syndromes. Therefore, Adiponectin has promising potential as a pharmacological agent.Recombinant mouse Adiponectin (rmAdiponectin) produced in E. coli is a single non-glycosylated polypeptide chain containing 227 amino acids. A fully biologically active molecule, rmAdiponectin has a molecular mass of 24.6 kDa analyzed by reducing SDS-PAGE.
Synonyms: Acrp-30, GBP-28, Apm-1 -
Molecular Weight
- 24.6 kDa, observed by reducing SDS-PAGE.
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UniProt
- Q60994
Target
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