FGF16 Protein (AA 2-207)
Quick Overview for FGF16 Protein (AA 2-207) (ABIN2017808)
Target
See all FGF16 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 2-207
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Characteristics
- Measured in a cell proliferation assay using 3T3 mouse fibroblast cell, The ED50 for this effect is < 20 ng/mL.
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Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Fibroblast Growth Factor 16 (FGF16) (AA 1-207) protein (His tag)
custom-made FGF16 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Fibroblast Growth Factor 16 (FGF16) (AA 1-207) protein (His tag)custom-made FGF16 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Fibroblast Growth Factor 16 (FGF16) (Active) proteinFGF16 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 16 (FGF16) (AA 1-207) protein (GST tag)FGF16 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant Human Fibroblast Growth Factor-16 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Fibroblast Growth Factor-16 should be stable up to 1 week at 4 °C or up to 3 months at -20 °C.
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Expiry Date
- 6 months
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- FGF16 (Fibroblast Growth Factor 16 (FGF16))
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Alternative Name
- Fibroblast Growth Factor-16 (FGF-16)
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Background
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Fibroblast Growth Factor-16 (FGF-16) is a heparin binding growth factor, a member of the FGF family. All FGF family members are heparin binding growth factors with a core 120 amino acid (aa) FGF domain that allows for a common tertiary structure. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The rat homolog is predominantly expressed in embryonic brown adipose tissue and has significant mitogenic activity, which suggests a role in proliferation of embryonic brown adipose tissue. FGF-16 is most similar to FGF-9 (73 % amino acid identity). The protein sequence of human FGF-16 displays 98.6 % identity with rat FGF-16. Chimpanzee FGF-16 (207 amino acids), chicken FGF-16 (207 amino acids), and zebrafish FGF-16 (203 amino acids) show 100 %, 89.9 %, and 79.2 % total amino acid identity with human FGF-16.Recombinant human FGF-16 produced in CHO cells is a polypeptide chain containing 206 amino acids. A fully biologically active molecule, rhFGF-16 has a molecular mass of 23 kDa analyzed by reducing SDS-PAGE.
Synonyms: FGF-16, Fibroblast Growth Factor-16, FGFG -
Molecular Weight
- 23 kDa, observed by reducing SDS-PAGE.
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UniProt
- O43320
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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