FGF18 Protein (AA 27-199)
Quick Overview for FGF18 Protein (AA 27-199) (ABIN2017816)
Target
See all FGF18 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 27-199
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Characteristics
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ED50 < 10 ng/mL, measured by a cell proliferation assay using 3T3 Cells, corresponding to a specific activity of > 1.0x 105 units/mg.
AA 27 -199, expressed with an N-terminal Met. -
Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Fibroblast Growth Factor 18 (FGF18) (Active) protein
FGF18 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 18 (FGF18) (AA 28-207) protein (His tag)FGF18 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 18 (FGF18) (AA 29-207) protein (GST tag)FGF18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant human Fibroblast Growth Factor-18 (rhFGF-18) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhFGF-18 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
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Expiry Date
- 6 months
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- FGF18 (Fibroblast Growth Factor 18 (FGF18))
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Alternative Name
- Fibroblast Growth Factor-18 (FGF-18)
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Background
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Fibroblast Growth Factor-18 (FGF-18) is a heparin-binding growth factor that is a member of the FGF family. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. FGF-18 plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. FGF-18 is required for normal ossification and bone development. It can also stimulate hepatic and intestinal proliferation.Recombinant human Fibroblast Growth Factor-18 (rhFGF-18) produced in E. coli is a single non-glycosylated polypeptide chain containing 174 amino acids. A fully biologically active molecule, rhFGF-18 has a molecular mass of 20.3 kDa analyzed by reducing SDS-PAGE.
Synonyms: Fibroblast Growth Factor-18, zFGF5, FGFI -
Molecular Weight
- 20.3 kDa, observed by reducing SDS-PAGE.
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UniProt
- O76093
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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