FGF18 Protein (AA 27-199)
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- Target See all FGF18 Proteins
- FGF18 (Fibroblast Growth Factor 18 (FGF18))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 27-199
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Characteristics
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ED50 < 10 ng/mL, measured by a cell proliferation assay using 3T3 Cells, corresponding to a specific activity of > 1.0x 105 units/mg.
AA 27 -199, expressed with an N-terminal Met. - Purity
- > 95 % by SDS-PAGE and HPLC analyses.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product FGF18 Protein
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Fibroblast Growth Factor 18 (FGF18) (Active) protein
FGF18 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 18 (FGF18) (AA 28-207) protein (His tag)FGF18 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 18 (FGF18) (AA 28-207) protein (His tag)FGF18 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 18 (FGF18) (AA 29-207) protein (GST tag)FGF18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 18 (FGF18) (AA 28-207) protein (His tag)Crystallography grade FGF18 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant human Fibroblast Growth Factor-18 (rhFGF-18) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhFGF-18 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- FGF18 (Fibroblast Growth Factor 18 (FGF18))
- Alternative Name
- Fibroblast Growth Factor-18 (FGF-18) (FGF18 Products)
- Synonyms
- FGF-18 Protein, ZFGF5 Protein, D130055P09Rik Protein, fgf18 Protein, FGF18 Protein, fgf18l Protein, fibroblast growth factor 18 Protein, fibroblast growth factor 18a Protein, fibroblast growth factor 18b Protein, FGF18 Protein, Fgf18 Protein, fgf18a Protein, Tsp_09844 Protein, fgf18b Protein
- Background
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Fibroblast Growth Factor-18 (FGF-18) is a heparin-binding growth factor that is a member of the FGF family. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. FGF-18 plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. FGF-18 is required for normal ossification and bone development. It can also stimulate hepatic and intestinal proliferation.Recombinant human Fibroblast Growth Factor-18 (rhFGF-18) produced in E. coli is a single non-glycosylated polypeptide chain containing 174 amino acids. A fully biologically active molecule, rhFGF-18 has a molecular mass of 20.3 kDa analyzed by reducing SDS-PAGE.
Synonyms: Fibroblast Growth Factor-18, zFGF5, FGFI - Molecular Weight
- 20.3 kDa, observed by reducing SDS-PAGE.
- UniProt
- O76093
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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