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IL-9 Protein (AA 19-144)

This Recombinant IL-9 protein is produced in CHO Cells.
Catalog No. ABIN2018029

Quick Overview for IL-9 Protein (AA 19-144) (ABIN2018029)

Target

See all IL-9 (IL9) Proteins
IL-9 (IL9) (Interleukin 9 (IL9))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 14
  • 8
  • 4
  • 2
  • 1
  • 1
  • 1
Human

Source

  • 13
  • 10
  • 2
  • 2
  • 2
  • 1
  • 1
CHO Cells

Purity

> 95 % as analyzed by SDS-PAGE and HPLC.
  • Protein Characteristics

    AA 19-144

    Characteristics

    ED50 < 1 ng/mL, measured in a cell proliferation assay using MO7e cells, corresponding to a specific activity of > 1x10^6 units/mg.

    Endotoxin Level

    < 0.2 EU/μg, determined by LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    Buffer

    Lyophilized after extensive dialysis against PBS.

    Storage

    -80 °C

    Storage Comment

    Lyophilized recombinant human Interlerkin 9 (IL-9) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-9 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    Expiry Date

    6 months
  • Target

    IL-9 (IL9) (Interleukin 9 (IL9))

    Alternative Name

    Interleukin 9 (IL-9)

    Background

    Interleukin 9, also known as IL9, is a cytokine (cell signalling molecule) belonging to the group of interleukins. The protein encoded by this gene is a cytokine produced by T-cells and specifically by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
    Synonyms: p40 cytokine, T-cell growth factor p40

    Molecular Weight

    25-40 kDa, observed by non-reducing SDS-PAGE.

    UniProt

    P15248

    Pathways

    JAK-STAT Signaling
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