IL-9 Protein (AA 19-144)
Quick Overview for IL-9 Protein (AA 19-144) (ABIN2018029)
Target
See all IL-9 (IL9) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 19-144
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Characteristics
- ED50 < 1 ng/mL, measured in a cell proliferation assay using MO7e cells, corresponding to a specific activity of > 1x10^6 units/mg.
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Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant human Interlerkin 9 (IL-9) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-9 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Expiry Date
- 6 months
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- IL-9 (IL9) (Interleukin 9 (IL9))
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Alternative Name
- Interleukin 9 (IL-9)
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Background
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Interleukin 9, also known as IL9, is a cytokine (cell signalling molecule) belonging to the group of interleukins. The protein encoded by this gene is a cytokine produced by T-cells and specifically by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Synonyms: p40 cytokine, T-cell growth factor p40 -
Molecular Weight
- 25-40 kDa, observed by non-reducing SDS-PAGE.
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UniProt
- P15248
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Pathways
- JAK-STAT Signaling
Target
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