CCL2 Protein (AA 24-96)
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- Target See all CCL2 Proteins
- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 24-96
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Origin
- Mouse
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Source
- HEK-293T Cells
- Characteristics
- The EC50 value of mouse MCP-1/CCL2 on Ca2+ mobilization assay in CHO-K1/Ga15/mCCR2 cells (human Ga15 and mouse CCR2 stably expressed in CHO-K1 cells) is less than 0.3 μg/mL.
- Purity
- > 98 % as analyzed by SDS-PAGE.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product CCL2 Protein
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Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) protein (His-Avi Tag,Biotin)
CCL2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) protein (His-Avi Tag)CCL2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) protein (His tag)CCL2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) protein (Fc Tag)CCL2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) (Active) protein (Biotin)CCL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA, FACS Active
Chemokine (C-C Motif) Ligand 2 (CCL2) protein (His tag)CCL2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) (Active) proteinCCL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 1-99) protein (GST tag)CCL2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-96), (partial) protein (His tag)CCL2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant Mouse MCP-1/CCL2 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Mouse MCP-1/CCL2 should be stable up to 1 week at 4 °C or up to 3 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
- Alternative Name
- MCP-1/CCL2 (CCL2 Products)
- Background
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Chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemotactic protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small cytokine that belongs to the CC chemokine family. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. CCL2 is implicated in the pathogeneses of several types of disease characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis and atherosclerosis. CCL2 is anchored in the plasma membrane of endothelial cells by glycosaminoglycan side chains of proteoglycans. CCL2 is primarily secreted by monocytes, macrophages and dendritic cells. CCL2 can signal through the CCR2 receptor.Recombinant mouse MCP-1/CCL2 produced in HEK293 cells is a polypeptide chain containing 73 amino acids. A fully biologically active molecule, r mMCP-1/CCL2 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE.
Synonyms: MCP-1, MCAF, JE, Monocyte Chemotactic Protein-1 (MCP-1), CCL2 - Molecular Weight
- 8 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q5SVU3
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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