CCL20 Protein (AA 27-96)
Quick Overview for CCL20 Protein (AA 27-96) (ABIN2018253)
Target
See all CCL20 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 27-96
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Characteristics
- The EC50 value of humanMIP-3 alpha/CCL20 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR6 cells (human Ga15 and human CCR6 stably expressed in CHO-K1 cells) is less than 200 ng/mL.
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Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Chemokine (C-C Motif) Ligand 20 (CCL20) protein (His tag)
CCL20 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 27-96) protein (His tag)CCL20 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 27-95) protein (GST tag)CCL20 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant Human MIP-3 alpha/CCL20 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human MIP-3 alpha/CCL20 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Expiry Date
- 6 months
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- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
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Alternative Name
- MIP-3 alpha/ccl20
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Background
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Chemokine (C-C motif) ligand 20 (CCL20) also known as liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3 alpha) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors.Recombinant humanMIP-3 alpha/CCL20 produced in CHO cells is a polypeptide chain containing 70 amino acids. A fully biologically active molecule, rhMIP-3 alpha/CCL20 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE.
Synonyms: MIP-3 alpha/CCL20, Human -
Molecular Weight
- 8 kDa, observed by reducing SDS-PAGE.
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UniProt
- P78556
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Pathways
- The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Target
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