VEGFD Protein (AA 89-205)
Quick Overview for VEGFD Protein (AA 89-205) (ABIN2018439)
Target
See all VEGFD (Figf) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 89-205
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Characteristics
- ED50 < 1 μg /mL, measured in a cell proliferation assay using HUVEC cells.
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Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) protein (His tag)
Figf Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 1-354) protein (GST tag)Figf Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 93-201) (Active) protein (His tag)Figf Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (AA 89-205), (full length) protein (GST tag)Figf Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant Human VEGF-D remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human VEGF-D should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Expiry Date
- 6 months
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- VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
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Background
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Vascular Endothelial Growth Factor (VEGF)-D, also known as c-Fos-induced growth factor (FIGF), is a member of the PDGF/VEGF growth factor family. It is expressed highly in lung, heart and small intestine, and at lower levels in skeletal muscle, colon and pancreas. It binds to VEGFR-2 and VEGFR-3 receptors and activates downstream signals. VEGF-D is a growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth. It is involved in many developmental and physiological processes including the formation of venous and lymphatic vascular systems during embryogenesis and the maintenance of differentiated lymphatic endothelium in adults. In tumor pathology, it has been reported to play a role in restructuring of lymphatic channels and regional lymph node metastasis.
Synonyms: Vascular Endothelial Growth Factor-D, FIGF -
Molecular Weight
- 18-19 kDa, observed by reducing SDS-PAGE.
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UniProt
- O43915
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Pathways
- RTK Signaling
Target
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