EBNA-1 Protein (GST tag)
Quick Overview for EBNA-1 Protein (GST tag) (ABIN2129003)
Target
See all EBNA-1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This EBNA-1 protein is labelled with GST tag.
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Characteristics
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Purified recombinant EBV EBNA1 protein
Expression System: E.coli
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Buffer
- 50 mM tris-HCl, pH 8.0, with 10 mM glutation, 60 mM NaCl and 0.5 % sarcosyl.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- EBNA-1 (Epstein-Barr Virus Nuclear Antigen-1 (EBNA-1))
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Alternative Name
- EBV EBNA1
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Target Type
- Viral Protein
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Background
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The Epstein-Barr virus (EBV), also called Human herpes virus 4 (HHV-4), is a virusof the herpes family (which includes Herpes simplex virusand Cytomegalo virus. On infecting the B-lymphocyte, the linear virus genome circularizes and the virus subsequently persists within the cell as an episome. The virus can execute several distinct programs of gene expressionwhich can be broadly categorized as being lytic cycle or latent cycle. The lytic cycleor productive infection results in staged expression of a host of viral proteinswith the ultimate objective of producing infectious virions. Formally, this phase of infection does not inevitably lead to lysis of the host cellas EBV virions are produced by budding from the infected cell. The latent cycle(lysogenic) programs are those that do not result in production of virions.
Alternative Names: Epstein Barr Nuclear Antigen 1 protein, EBV HHV4 EBNA1 protein, Epstein-Barr Virus EBNA 1 protein -
Molecular Weight
- 46 kDa (including GST tag of 26 kDa)
Target
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