IL-3 beta Protein

Catalog No. ABIN935528

This Recombinant IL-3 beta protein is produced in Escherichia coli (E. coli).

Quick Overview for IL-3 beta Protein (ABIN935528)

Target: IL-3 beta (Interleukin 3 beta (IL-3 beta))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: MISDRGSDAH HLLRTLDCRT IALEILVKLP YPQVSGLNNS DDKANLRNST LRRVNLDEFL KSQEEFDSQD TTDIKSKLQK LKCCIPAAAS DSVLPGVYNK DLDDFKKKLR FYVIHLKDLQ PVSVSRPPQP TSSSDNFRPM TVEC

Characteristics: Purified recombinant Human IL3 beta protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of thymidine uptake by Mouse MC-9 cells is 1.0 x 10^5 units/mg.

Sterility: 0.2 μm filtered

Endotoxin Level: < 0.1 ng per μg (1 EU/μg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Comment:

Biological activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of thymidine uptake by Mouse MC-9 cells is 1.0 x 10^5 units/mg.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in water to a concentration of 0.1-1.0 mg/mL. When dissolved, dilute further into aqueous buffered solutions.

Buffer: Sterile filtered through a 0.2 μm filter. Lyophilized from 5 mM Sodium Citrate pH 4.0.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Target Details

Target: IL-3 beta (Interleukin 3 beta (IL-3 beta))

Alternative Name: IL3 beta

Background: IL3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL3 may have additional immunoregulatory roles. Many of the IL3 activities depend upon co-stimulation with other cytokines. IL3 is species-specific, variably glycosylated cytokine.
Alternative Names: Multi-CSF protein, IL 3, IL 3 protein, IL-3 protein, IL-3 beta protein, HCGF protein, Mast cell growth factor protein, IL-3, MCGF protein, Interleukin 3 beta protein, P-cell stimulation factor protein, IL3

Molecular Weight: 16.3 kDa