CCL5 Protein
Quick Overview for CCL5 Protein (ABIN935753)
Target
See all CCL5 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS
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Characteristics
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Purified recombinant Mouse RANTES protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract total human lymph °Cyte population and total Mouse T cell population using a concentration range of 1.0-10.0 ng/mL. -
Endotoxin Level
- < 0.1 ng per μg (1 EU/μg) of RANTES.
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Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (Fc Tag)
CCL5 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (His tag,SUMO Tag)CCL5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (His-Avi Tag,Biotin)CCL5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) (Active) protein (Biotin)CCL5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 5 (CCL5) protein (His tag)CCL5 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) protein (Fc Tag)CCL5 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) (Active) protein (His tag)CCL5 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 1-91) protein (GST tag)CCL5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) (Active) proteinCCL5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Comment
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Biological activity: Determined by its ability to chemoattract total human lymph DEG Cyte population and total Mouse T cell population using a concentration range of 1.0-10.0 ng/mL.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Supplied lyophilized with no additives.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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Alternative Name
- RANTES
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Background
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RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV).
Alternative Names: Regulation upon Activation Normal T cell Express Sequence protein, SIS-delta protein, CCL5 protein -
Molecular Weight
- 7.8 kDa
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
Target
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