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BTLA Protein (AA 31-134) (Fc Tag)

Recombinant BTLA protein expressed in HEK-293 Cells.
Catalog No. ABIN2180655
$426.15
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Quick Overview for BTLA Protein (AA 31-134) (Fc Tag) (ABIN2180655)

Target

See all BTLA Proteins
BTLA (B and T Lymphocyte Associated (BTLA))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 23
  • 9
  • 2
  • 1
Human

Source

  • 26
  • 3
  • 2
  • 2
  • 1
  • 1
HEK-293 Cells

Purity

>92 % as determined by SDS-PAGE.
  • Protein Characteristics

    AA 31-134

    Purification tag / Conjugate

    This BTLA protein is labelled with Fc Tag.

    Sequence

    AA 31-134

    Characteristics

    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 38.7 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Tris with Glycine, Arginine and NaCl,  pH 7.5

    Handling Advice

    Please avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target

    BTLA (B and T Lymphocyte Associated (BTLA))

    Alternative Name

    BTLA

    Background

    B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.

    Molecular Weight

    38.7 kDa

    NCBI Accession

    NP_001078826

    Pathways

    Cancer Immune Checkpoints
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