BTLA Protein (AA 31-134) (Fc Tag)
Quick Overview for BTLA Protein (AA 31-134) (Fc Tag) (ABIN2180655)
Target
See all BTLA ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 31-134
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Purification tag / Conjugate
- This BTLA protein is labelled with Fc Tag.
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Sequence
- AA 31-134
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Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 38.7 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- BTLA (B and T Lymphocyte Associated (BTLA))
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Alternative Name
- BTLA
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Background
- B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
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Molecular Weight
- 38.7 kDa
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NCBI Accession
- NP_001078826
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Pathways
- Cancer Immune Checkpoints
Target
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