Transferrin Receptor Protein (AA 89-760) (His tag)
-
- Target See all Transferrin Receptor (TFRC) Proteins
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 89-760
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Transferrin Receptor protein is labelled with His tag.
- Sequence
- AA 89-760
- Characteristics
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 76 kDa. The protein migrates as 80-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Biological Activity Comment
- Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized rh CD71 /TFR at 10 μg/mL ( 100 μL/well ) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/mL.
- Top Product
- Discover our top product TFRC Protein
-
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (Fc Tag)
TFRC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transferrin Receptor (p90, CD71) (TFRC) protein (His-Avi Tag)TFRC Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His-Avi Tag,Biotin)TFRC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-763) protein (His tag)Crystallography grade TFRC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His tag)TFRC Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transferrin Receptor (p90, CD71) (TFRC) (AA 68-168) protein (GST tag)TFRC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (GST tag)TFRC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His-DYKDDDDK-Strep II Tag)TFRC Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Transferrin Receptor (p90, CD71) (TFRC) (AA 1-760) protein (Strep Tag)Crystallography grade TFRC Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Transferrin Receptor (p90, CD71) (TFRC) (AA 1-763) protein (Strep Tag)Crystallography grade TFRC Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
-
- Target
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Alternative Name
- CD71 (TFRC Products)
- Synonyms
- Trfr Protein, LOC100219280 Protein, tfr Protein, cd71 Protein, tfr1 Protein, trfr Protein, CD71 Protein, T9 Protein, TFR Protein, TFR1 Protein, TR Protein, TRFR Protein, p90 Protein, 2610028K12Rik Protein, AI195355 Protein, AI426448 Protein, AU015758 Protein, E430033M20Rik Protein, Mtvr-1 Protein, Mtvr1 Protein, transferrin receptor Protein, TFRC Protein, Tfrc Protein, tfrc Protein
- Background
- CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.
- Molecular Weight
- 77.0 kDa
- NCBI Accession
- NP_003225
- UniProt
- P02786
- Pathways
- Transition Metal Ion Homeostasis
-
