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Glypican 3 Protein (GPC3) (AA 25-559) (His tag)

This Recombinant Glypican 3 protein is expressed in HEK-293 Cells.
Catalog No. ABIN2181182

Quick Overview for Glypican 3 Protein (GPC3) (AA 25-559) (His tag) (ABIN2181182)

Target

See all Glypican 3 (GPC3) Proteins
Glypican 3 (GPC3)

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 22
  • 9
  • 9
  • 4
  • 1
Human

Source

  • 28
  • 9
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

>90 % as determined by SDS-PAGE.
  • Protein Characteristics

    AA 25-559

    Purification tag / Conjugate

    This Glypican 3 protein is labelled with His tag.

    Sequence

    AA 25-559

    Characteristics

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 61.7 kDa. The protein migrates as 40 kDa and 60-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation and associated via disulfide bonds.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 0.1 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Handling Advice

    Please avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target

    Glypican 3 (GPC3)

    Alternative Name

    Glypican 3

    Background

    Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.

    Molecular Weight

    61.7 kDa

    Pathways

    Glycosaminoglycan Metabolic Process
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