Glypican 3 Protein (GPC3) (AA 25-559) (His tag)
Quick Overview for Glypican 3 Protein (GPC3) (AA 25-559) (His tag) (ABIN2181182)
Target
See all Glypican 3 (GPC3) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 25-559
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Purification tag / Conjugate
- This Glypican 3 protein is labelled with His tag.
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Sequence
- AA 25-559
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Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 61.7 kDa. The protein migrates as 40 kDa and 60-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation and associated via disulfide bonds.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 0.1 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Glypican 3 (GPC3)
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Alternative Name
- Glypican 3
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Background
- Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
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Molecular Weight
- 61.7 kDa
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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