PTH1R Protein (AA 27-188) (His tag)

Catalog No. ABIN2181675

Recombinant PTH1R protein expressed in HEK-293 Cells.

Quick Overview for PTH1R Protein (AA 27-188) (His tag) (ABIN2181675)

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: >85 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 27-188

Purification tag / Conjugate: This PTH1R protein is labelled with His tag.

Sequence: AA 27-188

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.3 kDa. The protein migrates as 23-40 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Target Details

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Alternative Name: PTH1R

Background: Parathyroid hormone/parathyroid hormone-related peptide receptor is also known as Parathyroid hormone 1 receptor (PTH1R), PTHR1, PTH/PTHrP type I receptor (PTH/PTHr receptor), which belongs to the G-protein coupled receptor 2 family. PTH1R / PTHR1 is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.

Molecular Weight: 19.6 kDa

NCBI Accession: NP_000307

Pathways: Regulation of Carbohydrate Metabolic Process