PTH1R Protein (AA 37-175, Isoform 2) (His tag)
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- Target See all PTH1R Proteins
- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
- Protein Type
- Recombinant
- Protein Characteristics
- Isoform 2, AA 37-175
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PTH1R protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- AVSEHQLLHD KGKSIQDLRR RFFLHHLIAE IHTAEIRATS EVSPNSKPSP NTKNHPVRFG SDDEGRYLTQ ETNKVETYKE QPLKTPGKKK KGKPGKRKEQ EKKKRRTRSA WLDSGVTGSG LEGDHLSDTS TTSLELDSR
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product PTH1R Protein
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Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-134) protein (GST tag)
PTH1R Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-188) protein (His tag)Crystallography grade PTH1R Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Parathyroid Hormone 1 Receptor (PTH1R) (AA 464-593) protein (His tag)Crystallography grade PTH1R Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-188) protein (His tag)Crystallography grade PTH1R Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Parathyroid Hormone 1 Receptor (PTH1R) (AA 464-591) protein (His tag)Crystallography grade PTH1R Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-593) protein (rho-1D4 tag)Crystallography grade PTH1R Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-591) protein (rho-1D4 tag)Crystallography grade PTH1R Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
- Alternative Name
- PTHR (PTH1R Products)
- Synonyms
- PFE Protein, PTHR Protein, PTHR1 Protein, PPR Protein, Pthr Protein, Pthr1 Protein, pthr1 Protein, zPTH1R Protein, PTHrel Protein, PTH1 Protein, PTH Protein, parathyroid hormone 1 receptor Protein, parathyroid hormone 1 receptor a Protein, PTH1R Protein, Pth1r Protein, pth1ra Protein
- Background
- Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows th to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath . Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1-dependent manner through activation of Rac1.1 Publication
- Molecular Weight
- 19.8 kDa
- UniProt
- P12272
- Pathways
- Regulation of Carbohydrate Metabolic Process
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