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VEGF Protein (AA 27-190)

Recombinant VEGF protein expressed in HEK-293 Cells.
Catalog No. ABIN2181901

Quick Overview for VEGF Protein (AA 27-190) (ABIN2181901)

Target

See all VEGF Proteins
VEGF (Vascular Endothelial Growth Factor (VEGF))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 12
  • 5
  • 1
  • 1
Mouse

Source

  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

>95 % as determined by SDS-PAGE.

Grade

HPLC verified
  • Protein Characteristics

    AA 27-190

    Brand

    ActiveMax®

    Sequence

    AA 27-190

    Characteristics

    This protein carries no "tag". The protein has a calculated MW of 19.3 kDa. The protein migrates as 23-25 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Handling Advice

    Please avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target

    VEGF (Vascular Endothelial Growth Factor (VEGF))

    Alternative Name

    VEGF

    Background

    Vascular endothelial growth factor A (VEGFA) is also known as Vascular permeability factor (VPF). VEGFA belongs to the PDGF/VEGF growth factor family. VEGFA is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. VEGFA is produced by a group of three major isoforms as a result of alternative splicing and if any three isoforms are produced (VEGFA120, VEGFA164, and VEGFA188) then this will not result in vessel defects and death of the full VEGFA knockout in mice.

    Molecular Weight

    19.3 kDa
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