KIT Ligand Protein (KITLG)
Quick Overview for KIT Ligand Protein (KITLG) (ABIN2469042)
Target
See all KIT Ligand (KITLG) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MQEICRNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV THLSVSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVAC MEENAPKNVK ESLKKPETRN FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA
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Characteristics
- The ED50 was determined by the dose - dependent stimulation of the proliferation of the human TF - 1 cell line is < 10 ng/mL, corresponding to a specific activity of > 1 x 105 units/mg.
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Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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KIT Ligand (KITLG) (Active) protein
KITLG Origin: Human Host: Yeast (Pichia pastoris) > 95 % by SDS-PAGE Active
KIT Ligand (KITLG) (AA 26-214) protein (Fc Tag)KITLG Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
KIT Ligand (KITLG) protein (His tag)KITLG Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
KIT Ligand (KITLG) protein (His tag)KITLG Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
KIT Ligand (KITLG) (AA 26-189) protein (His tag)KITLG Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
KIT Ligand (KITLG) (AA 26-190) protein (His tag)KITLG Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
KIT Ligand (KITLG) (AA 26-189) protein (His-IF2DI Tag)KITLG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
KIT Ligand (KITLG) protein (His tag)KITLG Origin: Rat Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
KIT Ligand (KITLG) (AA 1-245) protein (GST tag)KITLG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
KIT Ligand (KITLG) (AA 26-189) (Active) proteinKITLG Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95% by SDS-PAGE SDS, AcA Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Handling Advice
- As with any protein, exposing SCF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Storage
- -20 °C
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Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted SCF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Expiry Date
- 24 months
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- KIT Ligand (KITLG)
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Alternative Name
- SCF
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Background
- Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant rat SCF is an 18.4 kDa polypeptide containing 154 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.
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Gene ID
- 60427
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NCBI Accession
- NP_068615
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OMIM
- 33667068
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UniProt
- P21581
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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