CD84 Protein (CD84) (His tag)
Quick Overview for CD84 Protein (CD84) (His tag) (ABIN2566447)
Target
See all CD84 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CD84 protein is labelled with His tag.
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Characteristics
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Measured in a cell proliferation assay using PHA stimulated human T cells in the presence of anti-CD3. The ED50 for this effect is typically 2-6 μg/mL in the presence of anti-CD3 immobilized at 20 ng/mL.
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Application Notes
- This recombinant protein can be used for WB. For research use only.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -80 °C,-20 °C
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Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- CD84
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Alternative Name
- CD84
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Background
- Leukocyte differentiation antigen CD84 is also known as SLAM family member 5 (SLAMF5), which belongs to immunoglobulin (Ig) superfamily. CD84 / SLAMF5 contains one Ig-like C2-type (immunoglobulin-like) domain. CD84 plays a role as adhesion receptor functioning by homophilic interactions and by clustering. CD84 / SLAMF5 increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway.
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Molecular Weight
- 23.6 kDa
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Gene ID
- 8832
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UniProt
- Q9UIB8
Target
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