LRRC4 Protein (His tag)
This Recombinant LRRC4 protein is expressed in HEK-293 Cells.
Catalog No. ABIN2566807
$708.13
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for LRRC4 Protein (His tag) (ABIN2566807)
Target
See all LRRC4 Proteins
LRRC4
(Leucine Rich Repeat Containing 4 (LRRC4))
Protein Type
Recombinant
Biological Activity
Active
Origin
Human
Source
HEK-293 Cells
Application
ELISA, Western Blotting (WB)
Purity
>92 % as determined by SDS-PAGE.
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Purification tag / Conjugate
- This LRRC4 protein is labelled with His tag.
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Characteristics
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Measured by its binding ability in a functional ELISA. Immobilized Recombinant mouse Netrin-G2a Fc chimera at 4 μg/mL, can bind rhLRRC4 with an apparent KD < 10 nM.
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Leucine Rich Repeat Containing 4 (LRRC4) (AA 39-527) protein (His tag)
LRRC4 Origin: Human Host: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE.
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Application Notes
- This recombinant protein can be used for WB, ELISA. For research use only.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -80 °C,-20 °C
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Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))
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Alternative Name
- NGL 2
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Background
- LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (NAG14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays a important role for auditory synaptic responses and involved in the suppression of glioma.
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Molecular Weight
- 55.6 kDa
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Gene ID
- 64101
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UniProt
- Q9HBW1
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Pathways
- Synaptic Membrane
Target
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