POFUT2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712347

Recombinant POFUT2 protein expressed in HEK-293 Cells.

Quick Overview for POFUT2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2712347)

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 3

Purification tag / Conjugate: This POFUT2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human POFUT2 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Alternative Name: Pofut2

Background: Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF MIM 131530)-like repeats or thrombospondin (THBS see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008].

Molecular Weight: 49.8 kDa

NCBI Accession: NP_598368