CTPS2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for CTPS2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2712616)
Target
See all CTPS2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This CTPS2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CTP synthase 2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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CTP Synthase II (CTPS2) (AA 1-586) protein (His tag)
custom-made CTPS2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CTP Synthase II (CTPS2) (AA 1-586) protein (GST tag)CTPS2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
CTP Synthase II (CTPS2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CTPS2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
CTP Synthase II (CTPS2) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)CTPS2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CTPS2 (CTP Synthase II (CTPS2))
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Alternative Name
- Ctp Synthase 2
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Background
- The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 65.5 kDa
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NCBI Accession
- NP_062831
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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