Cullin 3 Protein (CUL3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712631

This Recombinant Cullin 3 protein is expressed in HEK-293 Cells.

Quick Overview for Cullin 3 Protein (CUL3) (Myc-DYKDDDDK Tag) (ABIN2712631)

Target: Cullin 3 (CUL3)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This Cullin 3 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Cullin-3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Cullin 3 (CUL3)

Alternative Name: Cullin-3

Background: This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 88.7 kDa

NCBI Accession: NP_003581

Pathways: M Phase