Cyclin H Protein (CCNH) (Myc-DYKDDDDK Tag)
Quick Overview for Cyclin H Protein (CCNH) (Myc-DYKDDDDK Tag) (ABIN2712727)
Target
See all Cyclin H (CCNH) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Cyclin H protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Cyclin H protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Cyclin H (CCNH) (AA 1-323) protein (His tag)
custom-made CCNH Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cyclin H (CCNH) (AA 1-323) protein (His tag)custom-made CCNH Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cyclin H (CCNH) (AA 1-323) protein (GST tag)CCNH Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Cyclin H (CCNH)
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Alternative Name
- Cyclin H
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Background
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]
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Molecular Weight
- 37.5 kDa
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NCBI Accession
- NP_001230
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Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
Target
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