CYLD Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
(1 reference)Quick Overview for CYLD Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2712747)
Target
See all CYLD ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This CYLD protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CYLD (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 1-226) protein (His-IF2DI Tag)
CYLD Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Cylindromatosis (Turban Tumor Syndrome) (CYLD) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CYLD Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cylindromatosis (Turban Tumor Syndrome) (CYLD) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)CYLD Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "CaMKII mediates recruitment and activation of the deubiquitinase CYLD at the postsynaptic density." in: PLoS ONE, Vol. 9, Issue 3, pp. e91312, (2014) (PubMed).
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- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
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Alternative Name
- Cyld
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Background
- This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Molecular Weight
- 106.9 kDa
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NCBI Accession
- NP_001035814
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Pathways
- Apoptosis, Activation of Innate immune Response
Target
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