CYP2C8 Protein (Myc-DYKDDDDK Tag)
Quick Overview for CYP2C8 Protein (Myc-DYKDDDDK Tag) (ABIN2712766)
Target
See all CYP2C8 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CYP2C8 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CYP2C8 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) (AA 1-490) protein (His tag)
custom-made CYP2C8 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) (AA 1-490) protein (GST tag)CYP2C8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) (AA 115-282) protein (His-IF2DI Tag)CYP2C8 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CYP2C8 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))
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Alternative Name
- Cyp2c8
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Background
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene.
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Molecular Weight
- 55.6 kDa
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NCBI Accession
- NP_000761
Target
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