Factor XI Protein (Myc-DYKDDDDK Tag)
Quick Overview for Factor XI Protein (Myc-DYKDDDDK Tag) (ABIN2712928)
Target
See all Factor XI (F11) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Factor XI protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Coagulation factor XI (F11) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Coagulation Factor XI (F11) (AA 19-625) (Active) protein (His tag)
F11 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Coagulation Factor XI (F11) (AA 1-625) protein (GST tag)F11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Coagulation Factor XI (F11) (AA 19-387) protein (His tag)F11 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Factor XI (F11) (Coagulation Factor XI (F11))
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Background
- This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.
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Molecular Weight
- 69.9 kDa
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NCBI Accession
- NP_000119
Target
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