CASQ2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713078

This Recombinant CASQ2 protein is expressed in HEK-293 Cells.

Quick Overview for CASQ2 Protein (Myc-DYKDDDDK Tag) (ABIN2713078)

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This CASQ2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Calsequestrin-2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Alternative Name: Calsequestrin-2

Background: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.

Molecular Weight: 44.2 kDa

NCBI Accession: NP_001223

Pathways: Negative Regulation of Transporter Activity